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What is peripheral neuropathy?


Neuropathy is defined as a disease (pathos) of the nerves (neuro). Many symptoms are grouped together in the catch-all diagnosis. Whether it is called idiopathic (which means we don’t know the cause) or diabetic peripheral neuropathy (associated with diabetes), or poly neuropathy (which means “in many places”), they all have a singular common end cause. The nerves have begun to atrophy and miss fire because they have been deprived of oxygen (anoxia).

Anoxia causes Neuropathy

When your peripheral nerves are deprived of oxygen (anoxia), whether it is because of too much sugar or insulin in your blood, chemotherapeutic drugs, or toxins like metals and chemicals, these things can displace oxygen. Sometimes inflammation in the lower back or sciatic nerve area of the buttocks can restrict blood flow. Common drugs like statins (to reduce cholesterol) can eat away the myelin sheath of the nerves which is composed mostly of cholesterol. High blood pressure medicine can cause neuropathy by decreasing blood flow at the extremities, like the feet or hands.

In order to survive in this oxygen depleted environment, the nerve cells can temporarily shrink (atrophy) in order to present a smaller surface to the world and stay alive. Inside your body, each nerve cell is separated from the adjacent cell by a synaptic junction and the shrinking of each cell because of lack of oxygen can increase this gap. A larger gap makes it harder for the electrical nerve impulse to get across. With peripheral neuropathy, once this gap inhibits peripheral nerve impulses, the minerals that are dissolved in the synaptic junction's fluid can leach out and this makes the fluid less conductive. Water alone does not conduct electricity - water needs minerals dissolved in it to make it conductive.


Actual shrinkage of Nerve Cells Resulting in Widened Synaptic Junction


What causes lack of oxygen (anoxia)?

Lack of oxygen to the nerves can be caused by many different things:

  1. Temporary inflammations in the lower back which reduces blood flow to the nerves in the spinal column.
  2. Dramatic changes in glucose and insulin in the blood (diabetes) that displace oxygen.
  3. Side effects from drugs such as those for cholesterol, blood pressure and arthritis that change the metabolism of the nerves thus altering the way they use oxygen. (Pravachol) (Amytriptyline) (overdose)
  4. Toxins like metals, agent Orange, cleaning solvents and other environmental toxins that have a lot of free radicals that makes oxygen unusable for our cells.
  5. Chemotherapy that affects cancer and other fast growing or functioning cells like hair and nerves.
  6. Sciatic nerve entrapment (piriformis entrapment) caused from aging, muscles losing tone (becoming ropy or sinewy), and sitting too long in one position putting pressure on the sciatic nerve or its blood supply.
  7. Repeated trauma such as frostbite, standing on concrete, or accidents that change blood supply to the nerves.
  8. Surgery complications.
  9. Food Allergies  Specifically, the sweetener Aspartame.  This is very toxic to the body, including nerves and brain. As it metabolizes in the body, it transforms into Wood alcohol.  

All these triggers could result in a temporary reduction in local blood flow.  If you sit too long in an awkward position, you will notice that your nerves "go to sleep".  Once you move your limb around and restore the blood flow, the pins and needles and numbness, even pain disappears.  If this temporary restriction of blood flow continues too long or too often, this sensation can turn into neuropathy.

Sometimes this is because of a lower back or sciatic nerve problem, and temporary inflammation has pinched either the nerves, or the blood supply to the nerves. To survive, these nerves begin to atrophy (like an unused muscle) causing them to shrink back a little.  Normal nerve cells do not actually touch each other, but just get close.  The gaps between them are called synaptic junctions.  The nerve impulses travel along the body of the nerve cells, and they then have to jump this synaptic junction to reach the next nerve.  Some nerves may be almost a meter in length.  There are two primary types of nerve cells: afferent (to carry sensations to your brain), and efferent (or motor neurons to direct the movement of your muscles).  Some of these nerves are covered by a fatty, myelin sheath and others are not.

Some people are told they have a problem with this myelin sheath. That diagnosis can only be done via a biopsy (cutting the nerve and removing a portion of it), which destroys the nerve. You have to be careful not to accept the common catch all explanation of the cause of your neuropathy being from damage to the myelin sheath.  If your physician did not surgically remove a section of your nerve and send it to a lab for analysis, then the actual condition of your myelin sheath is unknown and probably just a guess. 

In order to get a better idea of how your nerves function, imagine a line of rubber bands laying end to end on a table.  The gap between them is similar to the synaptic junctions.  When the rubber bands shrink, the gaps get bigger.  When nerve cells are damaged, perhaps by a temporary restriction in their access to oxygen, they too atrophy or shrink a little, thus the synaptic junctions widens.  Just like with a spark plug in your car or lawn mower, if this gap gets too wide, the spark cannot make the jump. A normal sized nerve signal cannot jump this enlarged gap either, so the signal either does not get through or it gets misdirected to another part of the body and is misinterpreted as pain.

With fewer and fewer signals getting through these sleeping, smaller nerves, the nerves atrophy even more. The brain learns to ignore the erratic, misdirected signals so you feel numbness, or pins and needles.  Every once in a while, the nerve signals "pile up," and finally send a very large signal across these gaps which the brain interprets as sharp, stabbing, shooting pains.  

Although powerful drugs are sometimes prescribed to control pain (they do not work for numbness), they have severe side effects and can cause neuropathy to worsen over time.  Imagine your nerves as a bundle of telephone wires.  The center one is the one causing problems.  Drugs can work by inhibiting those "wires" that encircle this bad nerve so you do not feel it.  For a while this seems OK, but then those inhibited nerves go bad and you need more of the drug.  Finally all the nerves have been inhibited, the drug no longer works, and your symptoms are worse.  Manufacturers of certain dugs like Neurontin (Pfizer) have been fined millions of dollars by the government and are the subject of class action law suits.  Even seemingly safe drugs like Vioxx and other cox 2 inhibitors have had bad press about side effects like heart attacks.  For a list and description of other drugs related to neuropathy, email us.  (The ReBuilder has no side effects and is safe and comfortable.)


To remedy this situation, 4 things are needed:

1) a larger signal that can cross this synaptic junction,
2) minerals (electrolytes) to make the synaptic fluid more electrically conductive,
3) stimulation of nearby muscles to help local blood flow,
4) pain relief from safe, non-pharmaceutical stimulus.

(This is precisely what The ReBuilder system’s electrical stimulation is designed to do!)




Do you or a loved one suffer from peripheral neuropathy?

The road to recovery STARTS with the ReBuilder!
Aggressive Neuro-stimulus:  The ReBuilder

This amazing device is the closest thing to a cure you can find. The ReBuilder’s patented electrical signal device has been proven 94% effective in clinical studies in reducing painful symptoms of neuropathy.

FDA Approved  ♦  Covered by Most Plans with a Prescription 


Are You Suffering?


Did You Know?

20 million Americans suffer from peripheral neuropathy!

30% of cases, the cause is diabetes!
60-70% of diabetics have some nervous system damage in the U.S.
The annual medical expenses for diabetic neuropathy symptoms in the U.S. are as high as $13.7 billion annually.  (this does not include the other 70% of non diabetic cases!)


Relief Can Be Yours!

An amazing device called The ReBuilder, has helped over 100,000 people just like you.  Proven 94% effective in relieving and even reversing neuropathy symptoms, regardless of the cause!

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Statements made here about peripheral neuropathy have not been reviewed by the FDA. Statements about neuropathy and others topics are for information only and should not be used as a substitute for the advice of a physician or other licensed health care practitioner.